Introduction of arthritisjiu0 edited on2017-06-09 04:14:11 74 views
Introduction of arthritis
1. gouty arthritis
Gout is a metabolic disorder caused by abnormal purine metabolism and increased uric acid synthesis.
When renal dysfunction occurs, uric acid levels rise as a result of decreased uric acid clearance in the kidneys.
Uric acid in the plasma reaches saturation, causing sodium urate crystals to deposit in the relatively short vascular tissue around the distal joint.
The presence of such crystals can lead to acute inflammatory synovitis of either joint or joint.
Gout are more common in the male, toe is the most commonly affected region, from 50% to 70% in the first episode. 90% of gout patients suffer from the first metatarsophalangeal joint at some stage of their lives.
Other areas of the foot that may be affected include sufficient back, heels, and ankles.
2. ankylosing spondylitis
Many young men have obvious family tendency.
The axial joint, such as sacroiliac joint and spinal joint, is mainly involved, and peripheral joint involvement can also occur,
But most of them are characterized by asymmetric joint swelling and pain,
And often accompanied by spinous process, the big rotor, Achilles tendon, rib joint and other tendons and ligaments attachment pain.
Serious lesions can occur when the spine stiffness, cervical spine, lumbar spine, thoracic spine restricted activities,
There is a "hunchback" which seriously affects the daily life of the patient.
Most of the extra articular manifestations were iris, ciliary body inflammation, heart block, and aortic valve insufficiency
X-ray showed the sacroiliac joint invasion, destruction or fusion.
More than 90% of patients had HLA-B27 positive, while the rheumatoid factor was negative.
3. reactive arthritis
The disease has a very urgent onset. It usually has a history of intestinal or urinary tract infection before the onset of disease.
The involvement of large joints (especially lower limb joints) is mainly asymmetrical,
Generally asymmetrical, finger proximal, interphalangeal joints, wrist joints and other small joints.
May be associated with inflammation, urethritis, glans penis inflammation and fever,
HLA-B27 is positive while rheumatoid factor is negative,
The patient presented with an X-ray change in asymmetric sacroiliac joint.
4. infectious arthritis
Relating to bacterial infection. Common pathogens include Staphylococcus aureus and Streptococcus pneumoniae,
Neisseria meningitidis, Neisseria gonorrhoeae, Streptococcus, Mycobacterium tuberculosis.
The pathogenesis includes direct bacterial infection and the release of toxins or metabolites from the bacteria during infection
Pathogenic factors include subacute bacterial endocarditis, scarlet fever, arthritis, and so on.
Arthritis caused by direct bacterial infection is characterized by redness and swelling of the joints,
And joint dysfunction occurs. Asymmetric joint involvement of lower limb load.
Large joint involvement is common, such as hip and knee joints. The joint cavity fluid often presents the purulent change.
Smear or culture to find bacteria. TB arthritis affects young people,
There is evidence of tuberculosis in other areas, including tuberculosis of the lungs or lymph nodes.
Nodular erythema, serum rheumatoid factor negative. Positive tuberculin test.
Arthritis caused by bacterial metabolites or toxins can heal in 1~2 weeks,
The joint symptom is wandering.
Such as traumatic arthritis, psoriasis, arthritis, enteropathy arthritis, etc..
Autoimmune diseases, such as systemic lupus erythematosus and Sjogren's syndrome,
Scleroderma and tumors also occur in the course of the disease, the development of arthritis is also often manifested.
published on：20170609 04:14:11 guangzhou
category： Home Moisture
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